{"id":769752,"date":"2026-05-09T02:24:44","date_gmt":"2026-05-09T02:24:44","guid":{"rendered":"https:\/\/immunomart.com\/?post_type=product&p=769752"},"modified":"2026-05-09T19:23:45","modified_gmt":"2026-05-09T19:23:45","slug":"sox4-master-regulator-of-epithelial-mesenchymal-transition-sox4-2540-cf568-conjugate-0-1mg-ml-bt-a-bnc682540","status":"publish","type":"product","link":"https:\/\/immunomart.com\/product\/sox4-master-regulator-of-epithelial-mesenchymal-transition-sox4-2540-cf568-conjugate-0-1mg-ml-bt-a-bnc682540\/","title":{"rendered":"SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4\/2540), CF568 conjugate, 0.1mg\/mL"},"content":{"rendered":"<p>SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors with a critical role in embryonic development and in cell-fate determination during organogenesis of the heart, pancreas, brain, and in B and T lymphocyte differentiation. SOX4 gene expression is upregulated in many cancer types, and increased SOX4 activity contributes to cellular transformation, cell survival, and metastasis. Gene expression profiling has uncovered SOX4 with upregulated activity during TGF-\u03b2-induced epithelial-mesenchymal transition (EMT) in normal and cancerous breast epithelial cells. SOX4 is indispensable for EMT and cell survival in vitro and for primary tumor growth and metastasis in vivo. SOX4 is identified as a master regulator of EMT by governing the expression of the epigenetic modifier Ezh2.Primary antibodies are available purified, or with a selection of fluorescent CF\u00ae Dyes and other labels. CF\u00ae Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF\u00ae405S and CF\u00ae405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.<\/p>\n<div style=\"margin:18px 0 4px;padding:11px 14px;background:#fdf4f4;border:1px solid #e6bdbd;border-left:3px solid #c41e3a;border-radius:4px;font-size:13px;line-height:1.55;color:#3a3a3a;\"><strong style=\"color:#8a1524;\">For Research Use Only (RUO).<\/strong> This product is sold strictly for laboratory research use only. <strong>Not for human or veterinary consumption, therapeutic, or diagnostic use.<\/strong> Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors with a critical role in embryonic development and in cell-fate determination during organogenesis of the heart, pancreas, brain, and in B and T lymphocyte differentiation. SOX4 gene expression is upregulated in many cancer types, and increased SOX4 activity contributes to cellular transformation, [&hellip;]<\/p>\n","protected":false},"featured_media":720308,"template":"","meta":{"_acf_changed":false,"ep_exclude_from_search":false},"product_brand":[1638],"product_cat":[2339,2340,2341,2368],"product_tag":[],"class_list":{"0":"post-769752","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_brand-biotium","7":"product_cat-biotium-antibodies","8":"product_cat-cancer","9":"product_cat-developmental-biology","10":"product_cat-transcription-factors","11":"pa_antibody_type-primary","12":"pa_application-ffpe","13":"pa_application-ihc","14":"pa_clonality-monoclonal","15":"pa_conjugate-cf568","16":"pa_host-mouse","17":"pa_isotype-igg2b-kappa","18":"pa_localization-nucleus","19":"pa_product_class-primary-antibody","20":"pa_size-100-l","21":"pa_size-500-l","22":"pa_species_reactivity-human","24":"first","25":"instock","26":"taxable","27":"shipping-taxable","28":"purchasable","29":"product-type-variable"},"acf":[],"_links":{"self":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product\/769752","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media\/720308"}],"wp:attachment":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media?parent=769752"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_brand?post=769752"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_cat?post=769752"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_tag?post=769752"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}