{"id":767444,"date":"2026-05-09T01:52:30","date_gmt":"2026-05-09T01:52:30","guid":{"rendered":"https:\/\/immunomart.com\/?post_type=product&p=767444"},"modified":"2026-05-09T19:23:45","modified_gmt":"2026-05-09T19:23:45","slug":"sdhb-succinate-dehydrogenase-b-pheochromocytoma-markersdhb-2382-cf647-conjugate-0-1mg-ml-bt-a-bnc472382","status":"publish","type":"product","link":"https:\/\/immunomart.com\/product\/sdhb-succinate-dehydrogenase-b-pheochromocytoma-markersdhb-2382-cf647-conjugate-0-1mg-ml-bt-a-bnc472382\/","title":{"rendered":"SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker)(SDHB\/2382), CF647 conjugate, 0.1mg\/mL"},"content":{"rendered":"<p>Succinate dehydrogenase (SDH) is Complex II in the mitochondria, vital for mitochondrial electron transport, as well as Krebs cycle function. Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. The SDH complex functions as a tumor suppressor. Loss of any subunit proteins lead to destabilization of the complex and tumor formation. Antibody to SDHB is helpful in the identification of phaeochromocytomas, paragangliomas and GIST. Primary antibodies are available purified, or with a selection of fluorescent CF\u00ae Dyes and other labels. CF\u00ae Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF\u00ae405S and CF\u00ae405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.<\/p>\n<div style=\"margin:18px 0 4px;padding:11px 14px;background:#fdf4f4;border:1px solid #e6bdbd;border-left:3px solid #c41e3a;border-radius:4px;font-size:13px;line-height:1.55;color:#3a3a3a;\"><strong style=\"color:#8a1524;\">For Research Use Only (RUO).<\/strong> This product is sold strictly for laboratory research use only. <strong>Not for human or veterinary consumption, therapeutic, or diagnostic use.<\/strong> Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Succinate dehydrogenase (SDH) is Complex II in the mitochondria, vital for mitochondrial electron transport, as well as Krebs cycle function. Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. The SDH complex functions as a tumor [&hellip;]<\/p>\n","protected":false},"featured_media":721389,"template":"","meta":{"_acf_changed":false,"ep_exclude_from_search":false},"product_brand":[1638],"product_cat":[2339],"product_tag":[],"class_list":{"0":"post-767444","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_brand-biotium","7":"product_cat-biotium-antibodies","8":"pa_antibody_type-primary","9":"pa_clonality-monoclonal","10":"pa_conjugate-cf647","11":"pa_host-mouse","12":"pa_isotype-igg2b-kappa","13":"pa_localization-mitochondria","14":"pa_product_class-primary-antibody","15":"pa_size-100-l","16":"pa_size-500-l","17":"pa_species_reactivity-human","19":"first","20":"instock","21":"taxable","22":"shipping-taxable","23":"purchasable","24":"product-type-variable"},"acf":[],"_links":{"self":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product\/767444","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media\/721389"}],"wp:attachment":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media?parent=767444"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_brand?post=767444"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_cat?post=767444"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_tag?post=767444"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}