{"id":755672,"date":"2026-05-08T23:28:38","date_gmt":"2026-05-08T23:28:38","guid":{"rendered":"https:\/\/immunomart.com\/?post_type=product&p=755672"},"modified":"2026-05-09T19:23:45","modified_gmt":"2026-05-09T19:23:45","slug":"spectrin-beta-iii-sptbn2-sptbn2-1778-0-2mg-ml-bt-a-bnub1778","status":"publish","type":"product","link":"https:\/\/immunomart.com\/product\/spectrin-beta-iii-sptbn2-sptbn2-1778-0-2mg-ml-bt-a-bnub1778\/","title":{"rendered":"Spectrin beta III (SPTBN2) (SPTBN2\/1778), 0.2mg\/mL"},"content":{"rendered":"<p>Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I\/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin \u03b1 and spectrin\u03b2 are present in erythrocytes, whereas spectrin \u03b1 II (also designated fodrin \u03b1) and spectrin\u03b2 I (also designated fodrin\u03b2) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin\u03b2 III is highly homologous to both spectrin\u03b2 I and spectrin\u03b2 II. Spectrin\u03b2 III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.Primary antibodies are available purified, or with a selection of fluorescent CF\u00ae Dyes and other labels. CF\u00ae Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF\u00ae405S and CF\u00ae405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.<\/p>\n<div style=\"margin:18px 0 4px;padding:11px 14px;background:#fdf4f4;border:1px solid #e6bdbd;border-left:3px solid #c41e3a;border-radius:4px;font-size:13px;line-height:1.55;color:#3a3a3a;\"><strong style=\"color:#8a1524;\">For Research Use Only (RUO).<\/strong> This product is sold strictly for laboratory research use only. <strong>Not for human or veterinary consumption, therapeutic, or diagnostic use.<\/strong> Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I\/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin \u03b1 and spectrin\u03b2 are present [&hellip;]<\/p>\n","protected":false},"featured_media":721408,"template":"","meta":{"_acf_changed":false,"ep_exclude_from_search":false},"product_brand":[1638],"product_cat":[2339,2352],"product_tag":[],"class_list":{"0":"post-755672","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_brand-biotium","7":"product_cat-biotium-antibodies","8":"product_cat-cytoskeleton","9":"pa_antibody_type-primary","10":"pa_application-ffpe","11":"pa_application-if","12":"pa_application-ihc","13":"pa_application-wb","14":"pa_clonality-monoclonal","15":"pa_conjugate-unconjugated","16":"pa_host-mouse","17":"pa_isotype-igg1-kappa","18":"pa_localization-plasma-membrane","19":"pa_product_class-primary-antibody","20":"pa_purification-with-bsa","21":"pa_size-100-l","22":"pa_size-500-l","23":"pa_species_reactivity-human","25":"first","26":"instock","27":"taxable","28":"shipping-taxable","29":"purchasable","30":"product-type-variable"},"acf":[],"_links":{"self":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product\/755672","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media\/721408"}],"wp:attachment":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media?parent=755672"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_brand?post=755672"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_cat?post=755672"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_tag?post=755672"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}