{"id":754988,"date":"2026-05-08T23:20:55","date_gmt":"2026-05-08T23:20:55","guid":{"rendered":"https:\/\/immunomart.com\/?post_type=product&p=754988"},"modified":"2026-05-09T19:23:45","modified_gmt":"2026-05-09T19:23:45","slug":"p53-tumor-suppressor-protein-tp53-1739-cf740-conjugate-0-1mg-ml-bt-a-bnc741739","status":"publish","type":"product","link":"https:\/\/immunomart.com\/product\/p53-tumor-suppressor-protein-tp53-1739-cf740-conjugate-0-1mg-ml-bt-a-bnc741739\/","title":{"rendered":"p53 Tumor Suppressor Protein (TP53\/1739), CF740 conjugate, 0.1mg\/mL"},"content":{"rendered":"<p>The specificity of this monoclonal antibody to its intended target was validated by HuProt\u2122 Array, containing more than 19,000, full-length human proteins. Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. It is a tumor suppressor protein expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast, lung, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in many malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.Primary antibodies are available purified, or with a selection of fluorescent CF\u00ae Dyes and other labels. CF\u00ae Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF\u00ae405S and CF\u00ae405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.<\/p>\n<div style=\"margin:18px 0 4px;padding:11px 14px;background:#fdf4f4;border:1px solid #e6bdbd;border-left:3px solid #c41e3a;border-radius:4px;font-size:13px;line-height:1.55;color:#3a3a3a;\"><strong style=\"color:#8a1524;\">For Research Use Only (RUO).<\/strong> This product is sold strictly for laboratory research use only. <strong>Not for human or veterinary consumption, therapeutic, or diagnostic use.<\/strong> Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The specificity of this monoclonal antibody to its intended target was validated by HuProt\u2122 Array, containing more than 19,000, full-length human proteins. Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. It is a tumor suppressor protein expressed [&hellip;]<\/p>\n","protected":false},"featured_media":721441,"template":"","meta":{"_acf_changed":false,"ep_exclude_from_search":false},"product_brand":[1638],"product_cat":[2344,2339,2346],"product_tag":[],"class_list":{"0":"post-754988","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_brand-biotium","7":"product_cat-apoptosis","8":"product_cat-biotium-antibodies","9":"product_cat-tumor-suppressors","10":"pa_antibody_type-primary","11":"pa_application-ffpe","12":"pa_application-ihc","13":"pa_application-wb","14":"pa_clonality-monoclonal","15":"pa_conjugate-cf740","16":"pa_host-mouse","17":"pa_isotype-igg2a-kappa","18":"pa_localization-nucleus","19":"pa_product_class-primary-antibody","20":"pa_size-100-l","21":"pa_size-500-l","22":"pa_species_reactivity-human","24":"first","25":"instock","26":"taxable","27":"shipping-taxable","28":"purchasable","29":"product-type-variable"},"acf":[],"_links":{"self":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product\/754988","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media\/721441"}],"wp:attachment":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media?parent=754988"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_brand?post=754988"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_cat?post=754988"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_tag?post=754988"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}