{"id":748193,"date":"2026-05-08T19:20:21","date_gmt":"2026-05-08T19:20:21","guid":{"rendered":"https:\/\/immunomart.com\/?post_type=product&p=748193"},"modified":"2026-05-09T19:23:45","modified_gmt":"2026-05-09T19:23:45","slug":"pdcd1-pd1-cd279-programmed-cell-death-1-pdcd1-1410r-biotin-conjugate-0-1mg-ml-bt-a-bncb1410","status":"publish","type":"product","link":"https:\/\/immunomart.com\/product\/pdcd1-pd1-cd279-programmed-cell-death-1-pdcd1-1410r-biotin-conjugate-0-1mg-ml-bt-a-bncb1410\/","title":{"rendered":"PDCD1 \/ PD1 \/ CD279 (Programmed Cell Death 1) (PDCD1\/1410R), Biotin conjugate, 0.1mg\/mL"},"content":{"rendered":"<p>PD-1 (also known as Programmed Death 1, CD279, and PDCD1) is a negative regulatory T-cell surface receptor. PD-1 is a Type I transmembrane protein expressed on the plasma membrane of T-cells. It is a T-cell checkpoint protein, involved in preventing autoimmunity. Because binding of PD-1 by its ligands PD-L1 or PD-L2 has a suppressive effect on the immune system, inhibition of the PD-1\/PD-L1 pathway is a major strategy of immune-oncology therapies. PD-L1 is upregulated in certain cancers, and blocking PD-1 or PD-L1 can inhibit cancer growth.Primary antibodies are available purified, or with a selection of fluorescent CF\u00ae Dyes and other labels. CF\u00ae Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF\u00ae405S and CF\u00ae405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.<\/p>\n<div style=\"margin:18px 0 4px;padding:11px 14px;background:#fdf4f4;border:1px solid #e6bdbd;border-left:3px solid #c41e3a;border-radius:4px;font-size:13px;line-height:1.55;color:#3a3a3a;\"><strong style=\"color:#8a1524;\">For Research Use Only (RUO).<\/strong> This product is sold strictly for laboratory research use only. <strong>Not for human or veterinary consumption, therapeutic, or diagnostic use.<\/strong> Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>PD-1 (also known as Programmed Death 1, CD279, and PDCD1) is a negative regulatory T-cell surface receptor. PD-1 is a Type I transmembrane protein expressed on the plasma membrane of T-cells. It is a T-cell checkpoint protein, involved in preventing autoimmunity. Because binding of PD-1 by its ligands PD-L1 or PD-L2 has a suppressive effect [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"ep_exclude_from_search":false},"product_brand":[1638],"product_cat":[2344,2339,2340,2367],"product_tag":[],"class_list":{"0":"post-748193","1":"product","2":"type-product","3":"status-publish","5":"product_brand-biotium","6":"product_cat-apoptosis","7":"product_cat-biotium-antibodies","8":"product_cat-cancer","9":"product_cat-cancer-immunotherapy-immune-checkpoint","10":"pa_antibody_type-primary","11":"pa_application-ffpe","12":"pa_application-ihc","13":"pa_clonality-recombinant-monoclonal","14":"pa_conjugate-biotin","15":"pa_host-rabbit","16":"pa_isotype-igg","17":"pa_localization-plasma-membrane","18":"pa_product_class-primary-antibody","19":"pa_size-100-l","20":"pa_size-500-l","21":"pa_species_reactivity-human","23":"first","24":"instock","25":"taxable","26":"shipping-taxable","27":"purchasable","28":"product-type-variable"},"acf":[],"_links":{"self":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product\/748193","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/types\/product"}],"wp:attachment":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media?parent=748193"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_brand?post=748193"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_cat?post=748193"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_tag?post=748193"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}