{"id":747136,"date":"2026-05-08T07:02:03","date_gmt":"2026-05-08T07:02:03","guid":{"rendered":"https:\/\/immunomart.com\/?post_type=product&p=747136"},"modified":"2026-05-09T19:23:45","modified_gmt":"2026-05-09T19:23:45","slug":"topoisomerase-ii-alpha-proliferation-drug-resistance-marker-top2a-1361-cf740-conjugate-0-1mg-ml-bt-a-bnc741361","status":"publish","type":"product","link":"https:\/\/immunomart.com\/product\/topoisomerase-ii-alpha-proliferation-drug-resistance-marker-top2a-1361-cf740-conjugate-0-1mg-ml-bt-a-bnc741361\/","title":{"rendered":"Topoisomerase II alpha (Proliferation &#038; Drug-Resistance Marker) (TOP2A\/1361), CF740 conjugate, 0.1mg\/mL"},"content":{"rendered":"<p>This antibody recognizes a 170 kDa protein, which is identified as topoisomerase II\u03b1. It shows no cross-reaction with topoisomerase II\u03b2 or topoisomerase I. Topo II\u03b1 plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- &#038; M-phases in transformed and developmentally regulated normal cells. Topo II\u03b1 is also implicated in drug resistance of tumor cells.Primary antibodies are available purified, or with a selection of fluorescent CF\u00ae Dyes and other labels. CF\u00ae Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF\u00ae405S and CF\u00ae405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.<\/p>\n<div style=\"margin:18px 0 4px;padding:11px 14px;background:#fdf4f4;border:1px solid #e6bdbd;border-left:3px solid #c41e3a;border-radius:4px;font-size:13px;line-height:1.55;color:#3a3a3a;\"><strong style=\"color:#8a1524;\">For Research Use Only (RUO).<\/strong> This product is sold strictly for laboratory research use only. <strong>Not for human or veterinary consumption, therapeutic, or diagnostic use.<\/strong> Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>This antibody recognizes a 170 kDa protein, which is identified as topoisomerase II\u03b1. It shows no cross-reaction with topoisomerase II\u03b2 or topoisomerase I. Topo II\u03b1 plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"ep_exclude_from_search":false},"product_brand":[1638],"product_cat":[2339,2345],"product_tag":[],"class_list":{"0":"post-747136","1":"product","2":"type-product","3":"status-publish","5":"product_brand-biotium","6":"product_cat-biotium-antibodies","7":"product_cat-cell-cycle","8":"pa_antibody_type-primary","9":"pa_application-ffpe","10":"pa_application-if","11":"pa_application-ihc","12":"pa_application-wb","13":"pa_clonality-monoclonal","14":"pa_conjugate-cf740","15":"pa_host-mouse","16":"pa_isotype-igg2b-kappa","17":"pa_localization-nucleus","18":"pa_product_class-primary-antibody","19":"pa_size-100-l","20":"pa_size-500-l","21":"pa_species_reactivity-human","22":"pa_species_reactivity-mouse","24":"first","25":"instock","26":"taxable","27":"shipping-taxable","28":"purchasable","29":"product-type-variable"},"acf":[],"_links":{"self":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product\/747136","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/types\/product"}],"wp:attachment":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media?parent=747136"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_brand?post=747136"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_cat?post=747136"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_tag?post=747136"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}