{"id":746404,"date":"2026-05-08T06:53:03","date_gmt":"2026-05-08T06:53:03","guid":{"rendered":"https:\/\/immunomart.com\/?post_type=product&p=746404"},"modified":"2026-05-09T19:23:45","modified_gmt":"2026-05-09T19:23:45","slug":"fli1-ewing-s-sarcoma-endothelial-marker-fli1-1312-cf740-conjugate-0-1mg-ml-bt-a-bnc741312","status":"publish","type":"product","link":"https:\/\/immunomart.com\/product\/fli1-ewing-s-sarcoma-endothelial-marker-fli1-1312-cf740-conjugate-0-1mg-ml-bt-a-bnc741312\/","title":{"rendered":"FLI1 (Ewing s Sarcoma &#038; Endothelial Marker) (FLI1\/1312), CF740 conjugate, 0.1mg\/mL"},"content":{"rendered":"<p>This antibody recognizes a protein of 51 kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus.Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90% of Ewing s Sarcoma (EWS)\/Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11;22)(q24;q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi&#8217;s Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.Primary antibodies are available purified, or with a selection of fluorescent CF\u00ae Dyes and other labels. CF\u00ae Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF\u00ae405S and CF\u00ae405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.<\/p>\n<div style=\"margin:18px 0 4px;padding:11px 14px;background:#fdf4f4;border:1px solid #e6bdbd;border-left:3px solid #c41e3a;border-radius:4px;font-size:13px;line-height:1.55;color:#3a3a3a;\"><strong style=\"color:#8a1524;\">For Research Use Only (RUO).<\/strong> This product is sold strictly for laboratory research use only. <strong>Not for human or veterinary consumption, therapeutic, or diagnostic use.<\/strong> Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>This antibody recognizes a protein of 51 kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"ep_exclude_from_search":false},"product_brand":[1638],"product_cat":[2339,2340,2342,2368],"product_tag":[],"class_list":{"0":"post-746404","1":"product","2":"type-product","3":"status-publish","5":"product_brand-biotium","6":"product_cat-biotium-antibodies","7":"product_cat-cancer","8":"product_cat-immunology","9":"product_cat-transcription-factors","10":"pa_antibody_type-primary","11":"pa_application-wb","12":"pa_clonality-monoclonal","13":"pa_conjugate-cf740","14":"pa_host-mouse","15":"pa_isotype-igg","16":"pa_localization-nucleus","17":"pa_product_class-primary-antibody","18":"pa_size-100-l","19":"pa_size-500-l","20":"pa_species_reactivity-human","22":"first","23":"instock","24":"taxable","25":"shipping-taxable","26":"purchasable","27":"product-type-variable"},"acf":[],"_links":{"self":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product\/746404","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/types\/product"}],"wp:attachment":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media?parent=746404"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_brand?post=746404"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_cat?post=746404"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_tag?post=746404"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}