{"id":743018,"date":"2026-05-08T06:13:32","date_gmt":"2026-05-08T06:13:32","guid":{"rendered":"https:\/\/immunomart.com\/?post_type=product&p=743018"},"modified":"2026-05-09T19:23:45","modified_gmt":"2026-05-09T19:23:45","slug":"hla-a-mhc-i-108-2c5-cf647-conjugate-0-1mg-ml-bt-a-bnc471095","status":"publish","type":"product","link":"https:\/\/immunomart.com\/product\/hla-a-mhc-i-108-2c5-cf647-conjugate-0-1mg-ml-bt-a-bnc471095\/","title":{"rendered":"HLA-A (MHC I) (108-2C5), CF647 conjugate, 0.1mg\/mL"},"content":{"rendered":"<p>HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. This MAb is useful for HLA molecular typing of peripheral blood leukocytes as well as a large number of leukemic cell lines. It reacts with an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, -A28, -A29, -A30, -A31 and -Aw33). Its epitope maps between aa65-to-aa80 of thealpha1 domain of the HLA-A. This MAb recognizes an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, A28, -A29, -A30, -A31 and -Aw33). Furthermore, by testing its reactivity with HLA-A2 natural variants and mutants, the importance of amino acid residues 79 and\/or 80 of thealpha1 domain was demonstrated in the formation of an intralocus HLA-A determinant.Primary antibodies are available purified, or with a selection of fluorescent CF\u00ae Dyes and other labels. CF\u00ae Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF\u00ae405S and CF\u00ae405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.<\/p>\n<div style=\"margin:18px 0 4px;padding:11px 14px;background:#fdf4f4;border:1px solid #e6bdbd;border-left:3px solid #c41e3a;border-radius:4px;font-size:13px;line-height:1.55;color:#3a3a3a;\"><strong style=\"color:#8a1524;\">For Research Use Only (RUO).<\/strong> This product is sold strictly for laboratory research use only. <strong>Not for human or veterinary consumption, therapeutic, or diagnostic use.<\/strong> Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. This MAb is useful for HLA molecular typing of peripheral blood [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"ep_exclude_from_search":false},"product_brand":[1638],"product_cat":[2339,2340,2342,2358],"product_tag":[],"class_list":{"0":"post-743018","1":"product","2":"type-product","3":"status-publish","5":"product_brand-biotium","6":"product_cat-biotium-antibodies","7":"product_cat-cancer","8":"product_cat-immunology","9":"product_cat-mhc-antigens","10":"pa_antibody_type-primary","11":"pa_application-flow","12":"pa_application-if","13":"pa_application-ihc","14":"pa_application-ihc-frozen","15":"pa_application-ip","16":"pa_application-surface","17":"pa_clonality-monoclonal","18":"pa_conjugate-cf647","19":"pa_host-mouse","20":"pa_isotype-igg1-kappa","21":"pa_localization-plasma-membrane","22":"pa_product_class-primary-antibody","23":"pa_size-100-l","24":"pa_size-500-l","25":"pa_species_reactivity-human","27":"first","28":"instock","29":"taxable","30":"shipping-taxable","31":"purchasable","32":"product-type-variable"},"acf":[],"_links":{"self":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product\/743018","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/types\/product"}],"wp:attachment":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media?parent=743018"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_brand?post=743018"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_cat?post=743018"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_tag?post=743018"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}