{"id":730333,"date":"2026-05-08T03:50:07","date_gmt":"2026-05-08T03:50:07","guid":{"rendered":"https:\/\/immunomart.com\/?post_type=product&p=730333"},"modified":"2026-05-09T19:23:45","modified_gmt":"2026-05-09T19:23:45","slug":"estrogen-receptor-beta-1erb455-1mg-ml-bt-a-bnum0455","status":"publish","type":"product","link":"https:\/\/immunomart.com\/product\/estrogen-receptor-beta-1erb455-1mg-ml-bt-a-bnum0455\/","title":{"rendered":"Estrogen Receptor beta 1(ERb455), 1mg\/mL"},"content":{"rendered":"<p style=\"margin: 0 0 12px 0; font-size: 16px;\"><strong>Size:<\/strong> 50 \u00b5L<\/p>\n<p>Estrogen receptors (ER) are members of the steroid\/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even though they share many functional characteristics.Primary antibodies are available purified, or with a selection of fluorescent CF\u00ae Dyes and other labels. CF\u00ae Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF\u00ae405S and CF\u00ae405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.<\/p>\n<div style=\"margin:18px 0 4px;padding:11px 14px;background:#fdf4f4;border:1px solid #e6bdbd;border-left:3px solid #c41e3a;border-radius:4px;font-size:13px;line-height:1.55;color:#3a3a3a;\"><strong style=\"color:#8a1524;\">For Research Use Only (RUO).<\/strong> This product is sold strictly for laboratory research use only. <strong>Not for human or veterinary consumption, therapeutic, or diagnostic use.<\/strong> Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Size: 50 \u00b5L Estrogen receptors (ER) are members of the steroid\/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with [&hellip;]<\/p>\n","protected":false},"featured_media":718577,"template":"","meta":{"_acf_changed":false,"ep_exclude_from_search":false},"product_brand":[1638],"product_cat":[2339,2340,2354,2371],"product_tag":[],"class_list":{"0":"post-730333","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_brand-biotium","7":"product_cat-biotium-antibodies","8":"product_cat-cancer","9":"product_cat-endocrinology","10":"product_cat-nuclear-receptors","11":"pa_antibody_type-primary","12":"pa_application-ffpe","13":"pa_application-flow","14":"pa_application-ihc","15":"pa_application-intracellular","16":"pa_application-wb","17":"pa_clonality-monoclonal","18":"pa_conjugate-unconjugated","19":"pa_host-mouse","20":"pa_isotype-igg2a","21":"pa_localization-nucleus","22":"pa_product_class-primary-antibody","23":"pa_purification-bsa-free","24":"pa_species_reactivity-horse","25":"pa_species_reactivity-human","26":"pa_species_reactivity-monkey","27":"pa_species_reactivity-mouse","28":"pa_species_reactivity-pig","29":"pa_species_reactivity-rat","30":"pa_species_reactivity-sheep","32":"first","33":"instock","34":"taxable","35":"shipping-taxable","36":"purchasable","37":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product\/730333","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media\/718577"}],"wp:attachment":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media?parent=730333"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_brand?post=730333"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_cat?post=730333"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_tag?post=730333"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}