{"id":725388,"date":"2026-05-08T02:55:46","date_gmt":"2026-05-08T02:55:46","guid":{"rendered":"https:\/\/immunomart.com\/?post_type=product&p=725388"},"modified":"2026-05-09T19:23:45","modified_gmt":"2026-05-09T19:23:45","slug":"cytochrome-c-mitochondrial-marker6h2-b4-1mg-ml-bt-a-bnum0184","status":"publish","type":"product","link":"https:\/\/immunomart.com\/product\/cytochrome-c-mitochondrial-marker6h2-b4-1mg-ml-bt-a-bnum0184\/","title":{"rendered":"Cytochrome C (Mitochondrial Marker)(6H2.B4), 1mg\/mL"},"content":{"rendered":"<p style=\"margin: 0 0 12px 0; font-size: 16px;\"><strong>Size:<\/strong> 50 \u00b5L<\/p>\n<p>Cytochrome c is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.<\/p>\n<div style=\"margin:18px 0 4px;padding:11px 14px;background:#fdf4f4;border:1px solid #e6bdbd;border-left:3px solid #c41e3a;border-radius:4px;font-size:13px;line-height:1.55;color:#3a3a3a;\"><strong style=\"color:#8a1524;\">For Research Use Only (RUO).<\/strong> This product is sold strictly for laboratory research use only. <strong>Not for human or veterinary consumption, therapeutic, or diagnostic use.<\/strong> Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Size: 50 \u00b5L Cytochrome c is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"ep_exclude_from_search":false},"product_brand":[1638],"product_cat":[2344,2339],"product_tag":[],"class_list":{"0":"post-725388","1":"product","2":"type-product","3":"status-publish","5":"product_brand-biotium","6":"product_cat-apoptosis","7":"product_cat-biotium-antibodies","8":"pa_antibody_type-primary","9":"pa_application-flow","10":"pa_application-if","11":"pa_application-intracellular","12":"pa_clonality-monoclonal","13":"pa_conjugate-unconjugated","14":"pa_host-mouse","15":"pa_isotype-igg1-kappa","16":"pa_localization-mitochondria","17":"pa_product_class-primary-antibody","18":"pa_purification-bsa-free","19":"pa_species_reactivity-human","20":"pa_species_reactivity-mouse","21":"pa_species_reactivity-rat","23":"first","24":"instock","25":"taxable","26":"shipping-taxable","27":"purchasable","28":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product\/725388","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/types\/product"}],"wp:attachment":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media?parent=725388"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_brand?post=725388"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_cat?post=725388"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_tag?post=725388"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}