{"id":717837,"date":"2026-05-05T03:14:11","date_gmt":"2026-05-05T03:14:11","guid":{"rendered":"https:\/\/immunomart.com\/?post_type=product&p=717837"},"modified":"2026-05-05T03:14:11","modified_gmt":"2026-05-05T03:14:11","slug":"jc-1-iodide-salt","status":"publish","type":"product","link":"https:\/\/immunomart.com\/product\/jc-1-iodide-salt\/","title":{"rendered":"JC-1 (IODIDE SALT)"},"content":{"rendered":"<p>JC-1 (5,5&#8242;,6,6&#8242;-Tetrachloro-1,1&#8242;,3,3&#8242;-tetraethylbenzimidazolylcarbocyanine, iodide) is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. JC-1monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential. The monomer JC-1 has green fluorescence (&amp;lamba; <sub>Em<\/sub> = 527 nm), while the J-aggregates have red fluorescence (&amp;lamba; <sub>Em<\/sub> = 590 nm). Therefore, it is possible to use fluorescence ratioing technique to study mitochondrial membrane potentials. JC-1 is particularly useful for apoptosis studies. In apoptotic cells, the dye stays in the cytoplasm and fluoresces green. It has also been used in high throughput drug screening applications.\u00a0 \u00a0 Biotium offers JC-1 as either iodide salt or chloride salt. Both forms have identical spectral properties. The iodide salt is the more commonly used form, however some researchers may prefer the chloride salt because chloride is the most prevalent anion in biological systems.\u00a0 <\/p>\n<ul>\u00a0 <\/p>\n<li>\u03b5 (MeOH) = 190,000<\/li>\n<p>\u00a0 <\/p>\n<li>Red solid soluble in DMSO<\/li>\n<p>\u00a0 <\/p>\n<li>Store at 4\u00b0C and protect from light, especially in solution<\/li>\n<p>\u00a0 <\/p>\n<li>C<sub>25<\/sub>H<sub>27<\/sub>Cl<sub>4<\/sub>IN<sub>4<\/sub><\/li>\n<p>\u00a0 <\/p>\n<li>MW: 652<\/li>\n<p>\u00a0 <\/p>\n<li>[47729-63-5]<\/li>\n<p>\u00a0 <\/ul>\n<h3>Handling<\/h3>\n<p>Store with desiccant; Protect from light<\/p>\n<div style=\"margin:18px 0 4px;padding:11px 14px;background:#fdf4f4;border:1px solid #e6bdbd;border-left:3px solid #c41e3a;border-radius:4px;font-size:13px;line-height:1.55;color:#3a3a3a\"><strong style=\"color:#8a1524\">For Research Use Only (RUO).<\/strong> This product is sold strictly for laboratory research use only. <strong>Not for human or veterinary consumption, therapeutic, or diagnostic use.<\/strong> Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>JC-1 (5,5&#8242;,6,6&#8242;-Tetrachloro-1,1&#8242;,3,3&#8242;-tetraethylbenzimidazolylcarbocyanine, iodide) is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. JC-1monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential. The monomer JC-1 has green fluorescence (&amp;lamba; Em = 527 nm), while the J-aggregates have red fluorescence (&amp;lamba; [&hellip;]<\/p>\n","protected":false},"featured_media":715088,"template":"","meta":{"_acf_changed":false,"ep_exclude_from_search":false},"product_brand":[1638],"product_cat":[1665],"product_tag":[],"class_list":{"0":"post-717837","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_brand-biotium","7":"product_cat-dyes-for-mitochondria-other-organelles","9":"first","10":"instock","11":"taxable","12":"shipping-taxable","13":"purchasable","14":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product\/717837","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media\/715088"}],"wp:attachment":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media?parent=717837"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_brand?post=717837"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_cat?post=717837"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_tag?post=717837"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}