{"id":717834,"date":"2026-05-05T03:14:10","date_gmt":"2026-05-05T03:14:10","guid":{"rendered":"https:\/\/immunomart.com\/?post_type=product&p=717834"},"modified":"2026-05-05T03:14:10","modified_gmt":"2026-05-05T03:14:10","slug":"jc-1-chloride-salt","status":"publish","type":"product","link":"https:\/\/immunomart.com\/product\/jc-1-chloride-salt\/","title":{"rendered":"JC-1 (chloride salt)"},"content":{"rendered":"<p>JC-1 (5,5&#8242;,6,6&#8242;-Tetrachloro-1,1&#8242;,3,3&#8242;-tetraethylbenzimidazolylcarbocyanine chloride) is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion.JC-1 monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential. The monomer JC-1 has green fluorescence (&amp;lamba; <sub>Em<\/sub> = 527 nm),while the J-aggregates have red fluorescence (&amp;lamba; <sub>Em<\/sub> = 590nm). Therefore, it is possible to use the fluorescence ratio technique to study mitochondrial membrane potentials. JC-1 is particularly useful for apoptosis studies. In apoptotic cells, the dye stays in the cytoplasm and fluoresces green. It has also been used in high throughput drug screening applications.\u00a0 \u00a0 JC-1, iodide is the original salt form of the dye. Biotium developed JC-1 chloride salt for applications where iodide ion is not desired. JC-1 chloride may also have the advantage of being slightly more water soluble than the iodide salt.\u00a0 <\/p>\n<ul>\u00a0 <\/p>\n<li>\u03b5 (MeOH) = 190,000<\/li>\n<p>\u00a0 <\/p>\n<li>Red solid soluble in DMSO<\/li>\n<p>\u00a0 <\/p>\n<li>Store at 4\u00b0C and protect from light, especially in solution<\/li>\n<p>\u00a0 <\/p>\n<li>C<sub>25<\/sub>H<sub>27<\/sub>Cl<sub>5<\/sub>N<sub>4<\/sub><\/li>\n<p>\u00a0 <\/p>\n<li>MW: 561.5<\/li>\n<p>\u00a0 <\/ul>\n<h3>Handling<\/h3>\n<p>Store with desiccant; Protect from light<\/p>\n<div style=\"margin:18px 0 4px;padding:11px 14px;background:#fdf4f4;border:1px solid #e6bdbd;border-left:3px solid #c41e3a;border-radius:4px;font-size:13px;line-height:1.55;color:#3a3a3a\"><strong style=\"color:#8a1524\">For Research Use Only (RUO).<\/strong> This product is sold strictly for laboratory research use only. <strong>Not for human or veterinary consumption, therapeutic, or diagnostic use.<\/strong> Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>JC-1 (5,5&#8242;,6,6&#8242;-Tetrachloro-1,1&#8242;,3,3&#8242;-tetraethylbenzimidazolylcarbocyanine chloride) is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion.JC-1 monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential. The monomer JC-1 has green fluorescence (&amp;lamba; Em = 527 nm),while the J-aggregates have red fluorescence (&amp;lamba; Em [&hellip;]<\/p>\n","protected":false},"featured_media":715295,"template":"","meta":{"_acf_changed":false,"ep_exclude_from_search":false},"product_brand":[1638],"product_cat":[1665],"product_tag":[],"class_list":{"0":"post-717834","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_brand-biotium","7":"product_cat-dyes-for-mitochondria-other-organelles","9":"first","10":"instock","11":"taxable","12":"shipping-taxable","13":"purchasable","14":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product\/717834","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media\/715295"}],"wp:attachment":[{"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/media?parent=717834"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_brand?post=717834"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_cat?post=717834"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/immunomart.com\/wp-json\/wp\/v2\/product_tag?post=717834"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}