– Membrane-permeant AM ester form of Fluo-3 that can be loaded into cells via incubation. Because of the relatively low water solubility of the AM ester, Pluronic F-127, a mild detergent, is often used as a dispersing agent to facilitate dye loading. Fluo-3 AM ester itself does not bind Ca² , but it is readily hydrolyzed to Fluo-3 by endogenous esterases once the dye is inside the cells. An important application of Fluo-3 AM ester is its use in high throughput drug screening. 

 
• Orange red solid soluble in DMSO
 
• Store -20°C and protect from light, especially when in solution
 
• C₅₁H₅₀Cl₂N₂O₂₃
 
• MW: 1129.9
 
• [121714-22-5]

Handling

Store with desiccant; Protect from light